Funded Projects
Haplotypic Basis of Pyrethroid Resistance in California Aedes aegypti
This project investigates the genetic basis of insecticide resistance in California mosquito populations. We're using haplotype tagging approaches to identify resistance markers that can inform targeted control strategies.
Key Objectives:
- Map pyrethroid resistance haplotypes in California Aedes aegypti populations
- Develop rapid molecular diagnostics for resistance screening
- Create predictive models for resistance spread
Research Team:
PI: Luciano V. Cosme | Collaborators: PacVec, San Gabriel Valley and Northwest MVCDs
What Makes Some Mosquitoes Immune to Dengue? A Closer Look Inside Their Cells
Using single-cell approaches to understand why some mosquitoes are naturally resistant to dengue virus infection. This research could identify new targets for blocking virus transmission.
Research Approach:
- Single-cell RNA sequencing of infected mosquito tissues
- Identification of dengue resistance genes
- Functional validation using CRISPR gene editing
Feeding the Future: Robotics-Driven Vertical Insect Farming
An interdisciplinary collaboration developing automated mealworm farming systems to address sustainable protein production in Southern California. This groundbreaking project combines cutting-edge robotics with entomological expertise to revolutionize insect farming.
🔧 Technical Innovation:
- Computer vision for individual insect tracking
- Robotic arms with precision feeding mechanisms
- IoT sensor network for microclimate control
- Machine learning for growth optimization
- Automated waste-to-feed recycling system
🌱 SoCal Advantages:
- Year-round optimal temperatures
- Proximity to organic waste streams
- Growing market for sustainable protein
- Tech hub for robotics innovation
- Water-scarce region benefits from low-water protein
📊 Project Goals:
- 1,733g protein per m² per year production efficiency
- Fully automated from egg to harvest
- Zero-waste circular system
- Open-source control software
- Training facility for next-gen farmers
Research Team:
Co-PIs: Luciano V. Cosme (Entomology) & Jun Sheng (Mechanical Engineering)
Students: 1 Master's student | 2 Undergraduate students